Researchers at the US Department of Energy’s Brookhaven National Laboratory are delving into a groundbreaking concept called the “exocortex,” which aims to integrate artificial intelligence with human cognitive abilities, essentially extending the capabilities of scientists’ brains. This innovative idea envisions a network of AI agents specializing in various tasks such as handling scientific literature, orchestrating experiments, and data synthesis to enhance researchers’ cognitive reach. Despite the challenges ahead, such as advancing AI reliability and developing a seamless human-computer interface, the potential benefits for science and beyond are vast. The leader of the Electronic Nanomaterials Group emphasizes the importance of community collaboration in navigating this uncharted territory towards unlocking the full potential of AI-human synergy in research.